This paper develops a chemical stimulation method to sustain bioluminescence in living materials made from Pyrocystis lunula, enabling long-term, responsive light emission.

Science Advances · May 6, 2026Peer-reviewedBioengineering

An injectable soft implant for long-acting, reversible, ultra-stable release of therapeutics

Ceren Kütahya, Luca Panariello, Adrian Najer, Tatiana Rizou, André Shamsabadi, Giulia Brachi, David J. Peeler, Lukeriya Zharova, Thomas F. F. Fernandez Debets, Patrick Peschke, Anna P. Constantinou, Ruoxiao Xie, Yuxi Cheng, Ross Burdis, Alejandro Suárez‐Bonnet, , Molly M. Stevens

This paper develops an injectable hydrogel platform with poly(orthoester) microparticles for long-term, zero-order drug release, demonstrating in vitro and in vivo efficacy for up to 12 months.

bioRxiv · Feb 26, 2026 · PreprintBioengineering

Nanoscale biodegradable printing for designed tuneability of vaccine delivery kinetics

David J. Peeler, Rujie Sun, Ceren Kütahya, Patrick Peschke, Kun Li Zhou, Giulia Brachi, Jonathan Yeow, Omar Rifaie‐Graham, Jonathan P. Wojciechowski, Thomas F. F. Fernandez Debets, Vernon LaLone, Xin Song, Krunal Polra, Paul F. McKay, John S. Tregoning, , Molly M. Stevens

This paper develops a 3D printing method to create tunable drug delivery systems that control vaccine-induced antibody responses.

Advanced Materials · Feb 28, 2025Peer-reviewedBioengineering