Author

Claudia Canasto‐Chibuque

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-0787-5892Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1

Frequent Co-Authors

John H.J. PetriniiD· 3 shared Hexiao WangiD· 2 shared Jun Hyun KimiD· 2 shared Marcel Hohl· 2 shared Aitor GarziaiD· 1 shared Christina S. LeslieiD· 1 shared Diana Y. Eng· 1 shared Fiorella GhisaysiD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

John H.J. PetriniORCID

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3 papers

Recent·Most cited

Chronic Interferon Stimulated Gene Transcription Promotes Oncogene Induced Breast Cancer

Hexiao Wang, Claudia Canasto‐Chibuque, Jun Hyun Kim, Marcel Hohl, Christina S. Leslie, J. S. Reis-Filho, John H.J. Petrini

The paper shows that Mre11 deficiency leads to an ISG signature and chromatin changes, which are reversed by IFI205 ablation, promoting oncogene-induced breast cancer.

Genes & Development · Nov 1, 2024Peer-reviewedMolecular Biology

The MRE11-RAD50-NBS1 complex both starts and extends DNA end resection in mouse meiosis

Soonjoung Kim, Shintaro Yamada, Tao Li, Claudia Canasto‐Chibuque, Jun Hyun Kim, Marina Marcet-Ortega, Jiaqi Xu, Diana Y. Eng, Laura Feeney, John H.J. Petrini, Scott Keeney

This study shows the MRN complex is essential for both initiating and extending DNA end resection in mouse meiosis, with defects leading to spermatogenic failure.

bioRxiv · Aug 17, 2024 · PreprintGenetics

RTEL1 Influences the Abundance and Localization of TERRA RNA

Fiorella Ghisays, Aitor Garzia, Hexiao Wang, Claudia Canasto‐Chibuque, Marcel Hohl, Sharon A. Savage, Thomas Tuschl, John H.J. Petrini

This study shows that RTEL1 helicase regulates TERRA RNA abundance and localization, with implications for telomere stability and disease.

Nature Communications · May 21, 2021Peer-reviewedMolecular Biology