Chronic Interferon Stimulated Gene Transcription Promotes Oncogene Induced Breast Cancer
Hexiao Wang, Claudia Canasto‐Chibuque, Jun Hyun Kim, Marcel Hohl, Christina S. Leslie, J. S. Reis-Filho, John H.J. Petrini
The paper shows that Mre11 deficiency leads to an ISG signature and chromatin changes, which are reversed by IFI205 ablation, promoting oncogene-induced breast cancer.
Genes & Development · Nov 1, 2024Peer-reviewedMolecular Biology