Soonjoung Kim

The paper identifies adaptive hematopoietic and immune reprogramming in discordant monozygotic twins with intrauterine growth restriction through transcriptomic and epigenomic analyses.

The paper investigates how MRE11 suppresses germline mutagenesis at meiotic double-strand breaks in mice by analyzing the effects of DSB processing and end joining.

This study reconstitutes SPO11-dependent DNA double-strand break formation in vitro, revealing dimerization-dependent cleavage and topoisomerase activity.

This study shows the MRN complex is essential for both initiating and extending DNA end resection in mouse meiosis, with defects leading to spermatogenic failure.

The paper optimizes S1-seq for mapping meiotic DSBs and resection tracts in mouse spermatocytes and evaluates quantitative features of resection.

This study investigates the role of the ANKRD31-REC114 interaction in meiotic recombination and spermatogenesis, showing its critical importance for DSB formation, repair, and location in mice.