Dario Palmieri

Nucleolin acute degradation reveals novel functions in cell cycle progression and division in TNBC

This study uses the AID system with CRISPR/Cas9 to acutely degrade nucleolin in TNBC cells, revealing its role in cell cycle progression and division, and showing that its abrogation enhances the efficacy of mitotic inhibitors.

An in vivo 'turning model' reveals new RanBP9 interactions in lung macrophages.

This paper uses a novel mouse model to identify new RanBP9 interactions in lung macrophages, revealing its role in immune and metabolic functions.

A novel auxin-inducible degron system for rapid, cell cycle-specific targeted proteolysis

The paper introduces a new AID system that enables cell cycle-specific protein degradation, allowing study of protein roles in specific cell cycle phases.

In silico study predicts a key role of RNA-binding domains 3 and 4 in nucleolin-miRNA interactions.

This study predicts that RNA-binding domains 3 and 4 of nucleolin are critical for miRNA binding and processing, with implications for drug design targeting cancer-related pathways.

REMBRANDT: A high-throughput barcoded sequencing approach for COVID-19 screening.

REMBRANDT is a high-throughput sequencing method for rapid SARS-CoV-2 screening, capable of processing over 100,000 samples per day.