Vincenzo Coppola

The paper identifies a distal regulatory element controlling an eight-exon skipping event in MDM2, supporting a regulon model of alternative splicing in cancer.

This study uses the AID system with CRISPR/Cas9 to acutely degrade nucleolin in TNBC cells, revealing its role in cell cycle progression and division, and showing that its abrogation enhances the efficacy of mitotic inhibitors.

This paper uses a novel mouse model to identify new RanBP9 interactions in lung macrophages, revealing its role in immune and metabolic functions.

The paper introduces a new AID system that enables cell cycle-specific protein degradation, allowing study of protein roles in specific cell cycle phases.