Expanding the Tubulin Code: TTLL11 Polyglutamylase Drives Elongation of Primary Tubulin Chains
Jana Campbell, Miroslava Vošahlíková, Samar Ismail, Margareta Volnikova, L. Motlova, Julia Kudlacova, Kseniya Ustinova, Ivan Šnajdr, Zora Nováková, Miroslav Basta, Irina Gutsche, Marie‐Jo Moutin, Ambroise Desfosses, Cyril Bařinka
This study identifies TTLL11 as a polyglutamylase that extends primary tubulin chains, revealing a new mechanism in the tubulin code and its interaction with other tubulin modifications.
Science Advances · Aug 20, 2025Peer-reviewedBiochemistry