Marie‐Jo Moutin

This study identifies VASH1 phosphorylation by PRKG1 as a mechanism regulating tubulin detyrosination in DRG neurons through CNP signaling.

The paper identifies altered microtubule post-translational modifications in hypertrophic cardiomyopathy and shows protein kinase A modulates microtubule repolymerization in patient-derived hiPSC-CMs.

The paper shows that the SHANK3-CAMSAP2 interaction links synapses to dendritic microtubule organisation in parvalbumin neurons, with the SHANK3L68P mutation enhancing this interaction and altering microtubule dynamics.

This study identifies TTLL11 as a polyglutamylase that extends primary tubulin chains, revealing a new mechanism in the tubulin code and its interaction with other tubulin modifications.

This study shows that L-Dopa incorporation into tubulin alters microtubule dynamics and reduces dendritic spine density and excitatory synapses in neurons.

The paper shows that disrupting the balance of microtubule tyrosination and detyrosination in neurons leads to defects in axonal transport and AIS length.