Author

James A. Hemker

Stanford UniversityORCID 0000-0002-7598-8741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:Drosophila· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:long-read sequencing· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Bernard Y. KimiD· 2 shared Dmitri A. PetroviD· 2 shared Mark C. BitteriD· 2 shared Alan O. BerglandiD· 1 shared Egor LappoiD· 1 shared Erin A. MordecaiiD· 1 shared Hannah R. GellertiD· 1 shared Hayes OkeniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Bernard Y. KimORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pervasive fitness trade-offs revealed by rapid adaptation in large experimental populations of Drosophila melanogaster

Mark C. Bitter, Sharon I. Greenblum, S. Rajpurohit, Alan O. Bergland, James A. Hemker, Egor Lappo, Nicolas J. Betancourt, Susanne Tilk, Skyler Berardi, Hayes Oken, P. Schmidt, Dmitri A. Petrov

This study uses genomic data from Drosophila melanogaster to show how fitness trade-offs manifest under fluctuating selection, identifying genomic regions linked to reproduction and stress tolerance.

Ecology Letters · Mar 1, 2026Peer-reviewedEvolutionary Biology

Manual validation finds only ultra-long long-read sequencing enables faithful, population-level structural variant calling in Drosophila melanogaster euchromatin

James A. Hemker, Hannah R. Gellert, Jessica A. Rhodes, Bernard Y. Kim, Dmitri A. Petrov

The paper shows ultra-long long-read sequencing is needed for accurate structural variant calling in Drosophila melanogaster.

bioRxiv · Apr 21, 2025 · PreprintGenomics

Evolutionary adaptation under climate change: Aedes sp. demonstrates potential to adapt to warming

L. I. Couper, Tristram O. Dodge, James A. Hemker, Bernard Y. Kim, Moisés Expósito‐Alonso, Rachel B. Brem, Erin A. Mordecai, Mark C. Bitter

This study shows Aedes sierrensis has heritable genetic variation in heat tolerance that could allow it to adapt to warming faster than projected climate changes.

Proceedings of the National Academy of Sciences · Jan 7, 2025Peer-reviewedEvolutionary Biology