Author

Inmaculada Sanjuan-Ruiz

InsermORCID 0000-0002-0855-277XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Clotilde Lagier‐TourenneiD· 2 shared Gina Picchiarelli· 2 shared Luc DupuisiD· 2 shared Salim MegatiD· 2 shared Stéphane DieterleiD· 2 shared Sylvie Dirrig‐Grosch· 2 shared Albert Christian LudolphiD· 1 shared Anne‐Laurence BoutillieriD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Clotilde Lagier‐TourenneORCID

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2 papers

Recent·Most cited

NeuroscienceMolecular NeurodegenerationPeer-reviewedSep 6, 2021

Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation.

Inmaculada Sanjuan-Ruiz, Noé Govea-Perez, Melissa McAlonis‐Downes…·Luc Dupuis

This study shows that wild-type FUS rescues ALS-like disease caused by mutant FUS by activating an autoregulatory loop that reduces cytoplasmic mutant FUS levels.

21 citations

mouseexperimental assay

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NeuroscienceNature CommunicationsPeer-reviewedMay 21, 2021

Cytoplasmic accumulation of FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and defects in inhibitory synapses

Jelena Scekic‐Zahirovic, Inmaculada Sanjuan-Ruiz, Vanessa W. Y. Kan…·Luc Dupuis

This study shows that cytoplasmic FUS mislocalization in mice causes behavioral changes and inhibitory synaptic defects without widespread neuronal loss.

66 citationstop 4%

mousestatistical model

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