Molecular BiologyDrug DeliveryPeer-reviewed
Lipid Nanoparticles with Aptamers Enable Targeted mRNA Delivery to CD4⁺ T Cells
Shrey Shah, Meenakshi Ranasinghe, John Decker…·Sherwood Yao
This paper develops aptamer-functionalized lipid nanoparticles for targeted mRNA delivery to CD4+ T cells, showing enhanced in vitro transfection and in vivo tissue enrichment with safety profiles.