Author

Umut Berkay Altıntaş

University of British ColumbiaORCID 0000-0002-0861-5013Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Nathan A. LackiD· 2 shared Brad J. FortunatoiD· 1 shared Cathy Beatrice MoelansiD· 1 shared Chia-Chi Flora HuangiD· 1 shared Claudia GiambartolomeiiD· 1 shared Doğancan ÖzturaniD· 1 shared Elif Yapıcı· 1 shared Faraz HachiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Nathan A. LackORCID

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2 papers

Recent·Most cited

Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription

Umut Berkay Altıntaş, Ji-Heui Seo, Claudia Giambartolomei, Doğancan Özturan, Brad J. Fortunato, Geoffrey M. Nelson, Seth Raphael Goldman, Karen Adelman, Faraz Hach, Matthew L. Freedman, Nathan A. Lack

The paper investigates how AR-bound CREs influence gene expression through epigenetic changes and chromatin looping, finding that contact frequency with promoters drives expression.

Nature Communications · Nov 3, 2024Peer-reviewedGenomics

Breast cancer risk SNPs converge on estrogen receptor binding sites commonly shared between breast tumors to locally alter estrogen signalling output

Stacey E. P. Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Donaldson Collier, Tunç Morova, Umut Berkay Altıntaş, Yongsoo Kim, Sander Canisius, Cathy Beatrice Moelans, P. J. van Diest, Gözde Korkmaz, Nathan A. Lack, , Wilbert T. Zwart

The paper identifies breast cancer risk SNPs that overlap with estrogen receptor binding sites, showing their role in altering estrogen signaling through chromatin interactions.

Genome Research · May 6, 2024Peer-reviewedGenomics