Author
Harvard UniversityORCID 0000-0001-5096-3778Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Hina Sultana, Vasudha Vandadi, Harmony R. Salzler…·A. Gregory Matera
The paper identifies H3K36 methylation as critical for maintaining transcriptome fidelity in metazoans by suppressing aberrant initiation in heterochromatin.
Edward A. Gonzalez, Dahui Wang, Maciej Jeziorek…·Jean‐Pierre Etchegaray
This study shows that disrupting circadian rhythms through pluripotency factors and transcriptional pausing promotes cancer stem cell enrichment in TNBC, correlating with poor patient outcomes.
Travis J. Fleming, Mateusz Antoszewski, Sander Lambo…·Vijay G. Sankaran
This study identifies MECOM's role in blocking differentiation via CEBPA repression, showing that targeting this regulatory element can promote differentiation and reduce leukemia burden in AMLs.
Jorge Diego Martin-Rufino, Alexis Caulier, Seayoung Lee…·Vijay G. Sankaran
The paper identifies TF-sensitive chromatin regions as highly enriched for heritability of blood cell phenotypes, using a novel single-cell multi-omics approach.
Umut Berkay Altıntaş, Ji-Heui Seo, Claudia Giambartolomei…·Nathan A. Lack
The paper investigates how AR-bound CREs influence gene expression through epigenetic changes and chromatin looping, finding that contact frequency with promoters drives expression.