Author

P. J. van Diest

University Medical Center UtrechtORCID 0000-0003-0658-2745Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

P. J. van Diest3 papers

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Ana Marques· 1 shared Ana Rita Araujo· 1 shared Andreia G. Silva· 1 shared Anne-Marie FortieriD· 1 shared Antoine A KhaliliD· 1 shared Bruno CavadasiD· 1 shared Bruno S. Monteiro· 1 shared Carolien ElshoutiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Ana Marques

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 2, 2026

DDX3 Regulates the Innate Immune Response to Bone Sarcomas

Rachel Weil, Esteban Uceda Arias-Stella, Da Peng…·David Mark Loeb

This study shows that inhibiting DDX3 in sarcomas induces a Type I interferon response and reduces metastasis when combined with immunostimulant therapy in mouse models.

DOI 10.64898/2026.07.01.735844

mouseexperimental assay

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Cancer BiologybioRxivPreprintDec 21, 2025

Multi-omics analysis of TNBC organoids identifies phosphorylation of the membrane trafficking machinery as a key event associated with FER-mediated invasion

Carolien Elshout, Goncalo Mota, Joana Cunha…·Sandra Tavares

The paper identifies phosphorylation of membrane trafficking regulators, particularly SEC16A, as key to FER-mediated invasion in TNBC organoids.

DOI 10.64898/2025.12.18.695070

humanproteomics

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GenomicsGenome ResearchPeer-reviewedMay 6, 2024

Breast cancer risk SNPs converge on estrogen receptor binding sites commonly shared between breast tumors to locally alter estrogen signalling output

Stacey E. P. Joosten, Sebastian Gregoricchio, Suzan Stelloo…·Wilbert T. Zwart

The paper identifies breast cancer risk SNPs that overlap with estrogen receptor binding sites, showing their role in altering estrogen signaling through chromatin interactions.

5 citations

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