Author

Doğancan Özturan

University of British ColumbiaORCID 0000-0003-0562-8537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Nathan A. LackiD· 3 shared Alişan KayaböleniD· 1 shared Anne M. HaegertiD· 1 shared Berna ÖzeriD· 1 shared Brad J. FortunatoiD· 1 shared Canan BayraktariD· 1 shared Cem AlbayrakiD· 1 shared Claudia GiambartolomeiiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

Nathan A. LackORCID

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3 papers

Recent·Most cited

Cancer BiologyGenome MedicinePeer-reviewedOct 28, 2026

Longitudinal single-cell RNA sequencing of a neuroendocrine transdifferentiation model reveals transcriptional reprogramming in treatment-induced neuroendocrine prostate cancer

Funda Sar, Hee Chul Chung, Yen‐Yi Lin…·Colin C. Collins

This study uses longitudinal scRNA-seq to track neuroendocrine transdifferentiation in a prostate cancer model, identifying transcriptional changes and key regulators during treatment-induced NEPC progression.

5 citationstop 2%

mousescRNA-seq

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GenomicsNature CommunicationsPeer-reviewedNov 3, 2024

Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription

Umut Berkay Altıntaş, Ji-Heui Seo, Claudia Giambartolomei…·Nathan A. Lack

The paper investigates how AR-bound CREs influence gene expression through epigenetic changes and chromatin looping, finding that contact frequency with promoters drives expression.

21 citations

humanbulk RNA-seq

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Molecular BiologyAdvanced SciencePeer-reviewedJul 27, 2022

Protein scaffold-based multimerization of soluble ACE2 efficiently blocks SARS-CoV-2 infection in vitro and in vivo

Alişan Kayabölen, Uğur Akcan, Doğancan Özturan…·Tugba Bagci Onder

The paper develops multimeric sACE2 decoys using SunTag or MoonTag systems, showing >100-fold increased SARS-CoV-2 neutralization compared to monomeric sACE2.

16 citations

humanmouse

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