Aleix Rius Rigau

Spatial proteomic profiling of cardiac stromal populations and microenvironments in systemic sclerosis-associated primary myocardial involvement

The paper uses spatial proteomic profiling to analyze cardiac stromal populations and microenvironments in systemic sclerosis-associated myocarditis, identifying distinct fibroblast subtypes and their spatial interactions.

Distinct myeloid precursors and their interaction with mesenchymal cells orchestrate the spreading of psoriatic disease from the skin to the joints

The paper identifies a unique myeloid precursor population that facilitates the spread of psoriatic inflammation from skin to joints, interacting with fibroblasts to regulate T cell IL-17 expression.

Single cell mapping of the metabolic landscape of skin fibrosis in systemic sclerosis

The paper maps the metabolic landscape of skin fibrosis in systemic sclerosis using single-cell analysis and identifies metabolically active cell types and their interactions.

Mapping spatially-resolved transcriptomes in systemic sclerosis

The paper maps spatially-resolved transcriptomes in systemic sclerosis to identify a fibrotic niche and disease-specific cell states, linking them to clinical outcomes.