Tim Filla

The paper uses spatial proteomic profiling to analyze cardiac stromal populations and microenvironments in systemic sclerosis-associated myocarditis, identifying distinct fibroblast subtypes and their spatial interactions.

This study identifies spatially distinct fibroblast subpopulations and niches in human myocardial fibrosis across different disease states and their associations with fibrotic remodeling and cardiac dysfunction.

This study uses blood vessel organoids to model systemic sclerosis vasculopathy and fibrosis, showing that SSc serum induces epigenetic and molecular changes linked to endothelial dysfunction and potential therapeutic targets.

The paper uses spatial transcriptomic methods to identify novel fibroblast subpopulations in systemic sclerosis skin and their pathogenic roles.

The paper maps the metabolic landscape of skin fibrosis in systemic sclerosis using single-cell analysis and identifies metabolically active cell types and their interactions.