Author

Masaya Arai

Immunology Frontier Research Center, The University of OsakaORCID 0000-0002-0876-7842Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Atsushi SugimotoiD· 2 shared Norihisa MikamiiD· 2 shared Ryoji KawakamiiD· 2 shared Shimon SakaguchiiD· 2 shared Daisuke MotookaiD· 1 shared Naganari OhkuraiD· 1 shared Tomiko KimotoiD· 1 shared Yamami NakamuraiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Atsushi SugimotoORCID

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2 papers

Recent·Most cited

Generation of antigen-specific and functionally stable Treg cells from effector/memory T cells for cell therapy of immunological diseases

Norihisa Mikami, Ryoji Kawakami, Atsushi Sugimoto, Masaya Arai, Shimon Sakaguchi

This study converts effector/memory T cells into antigen-specific, functionally stable Tregs for immunological disease treatment.

bioRxiv · Jun 13, 2025 · PreprintImmunology

Oral antigen exposure under co-stimulation blockade generates Treg cells to establish immune tolerance despite prior sensitization

Masaya Arai, Ryoji Kawakami, Yamami Nakamura, Yoko Naito, Daisuke Motooka, Atsushi Sugimoto, Tomiko Kimoto, Naganari Ohkura, Norihisa Mikami, Shimon Sakaguchi

This study shows that oral antigen exposure with co-stimulation blockade generates stable regulatory T cells in antigen-sensitized mice, establishing long-term immune tolerance.

bioRxiv · Apr 2, 2025 · PreprintImmunology