Pere Puigserver

This study shows that cardiomyocyte PGC-1α is essential for cardiac adaptation to endurance exercise by suppressing GDF15 and preventing cardiac atrophy in mice.

This study identifies riboflavin as a critical metabolic dependency in acute myeloid leukemia, showing its role in nucleotide biosynthesis and iron-sulfur cluster metabolism beyond energy production.

This study identifies a cold-induced conformation of respiratory complex CI:III2 using cryo-EM and simulations, revealing structural changes that enhance electron transfer efficiency in cold environments.