Integration of human organoids single-cell transcriptomic profiles and human genetics repurposes critical cell type-specific drug targets for severe COVID-19
Yunlong Ma, Yijun Zhou, Dingping Jiang, Wei Dai, Jinɡjinɡ Li, Chunyu Deng, Chen Cheng, Gongwei Zheng, Yaru Zhang, Fei Qiu, Haojun Sun, Shilai Xing, Haijun Han, Jia Qu, Nan Wu, , Jianzhong Su
The paper integrates human organoid scRNA-seq data with GWAS and gene-drug interaction data to identify cell type-specific drug targets for severe COVID-19.
Cell Proliferation · Oct 8, 2023Peer-reviewedGenetic & Genomic Medicine