Cancer BiologybioRxivPreprint
Cyclin-dependent kinase 9 inhibitors as oncogene signaling modulators in combination with targeted therapy for the treatment of colorectal cancer
Mahshid Mohammadi, Muzaffer Ahmed Bhat, T. Li…·Chaoyuan Kuang
This study evaluates CDK9 inhibitors in CRC models, showing potent anti-proliferative effects and synergy with MEK inhibitors, suggesting a potential combination therapy for CRC.
DOI 10.1101/2025.08.13.669992