NeurosciencebioRxivPreprint
Disease related changes in ATAC-Seq of more than 450 iPSC-derived motor neuron lines from ALS patients and controls
Stanislav Tsitkov, Kelsey Valentine, Velina Kozareva…·Ernest Fraenkel
The paper analyzes ATAC-seq data from iPSC-derived motor neurons of ALS patients and controls to identify disease-specific chromatin accessibility changes and their predictive power for disease progression.