Author

Aaron P. Frank

Cedars-Sinai Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Clive Niels SvendseniD· 2 shared Ernest FraenkeliD· 2 shared Jeffrey D. RothsteiniD· 2 shared Jennifer E. Van EykiD· 2 shared Leslie Michels ThompsoniD· 2 shared Steven M. FinkbeineriD· 2 shared Susan LeiiD· 2 shared Alex Lenail· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Clive Niels SvendsenORCID

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2 papers

Recent·Most cited

Disease related changes in ATAC-Seq of more than 450 iPSC-derived motor neuron lines from ALS patients and controls

Stanislav Tsitkov, Kelsey Valentine, Velina Kozareva, Aneesh Donde, Aaron P. Frank, Susan Lei, Jennifer E. Van Eyk, Steven M. Finkbeiner, Jeffrey D. Rothstein, Leslie Michels Thompson, Dhruv Sareen, Clive Niels Svendsen, Ernest Fraenkel

The paper analyzes ATAC-seq data from iPSC-derived motor neurons of ALS patients and controls to identify disease-specific chromatin accessibility changes and their predictive power for disease progression.

bioRxiv · Sep 11, 2023 · PreprintNeuroscience

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

Loren Ornelas, Emilda Gomez, Lindsay Panther, Aaron P. Frank, Susan Lei, Berhan Mandefro, Maria G. Bañuelos, Brandon Shelley, Julia Kaye, Leandro de Araújo Lima, Stacia K. Wyman, Ryan G. Lim, Jie Wu, Jennifer T. Stocksdale, Malcolm Casale, , Leslie Michels Thompson

The paper performs an integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients to identify dysregulated pathways and validate them in vivo and in postmortem data.

bioRxiv · Nov 1, 2020 · PreprintNeuroscience