Author

Jason B. Cross

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-0919-2833Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Assay:structural biology· 1

Frequent Co-Authors

Brandon NovyiD· 2 shared Christoph H. BorchersiD· 2 shared Edith Nagy· 2 shared Evgeniy V. PetrotchenkoiD· 2 shared Roopa ThapariD· 2 shared Foroughsadat Absar· 1 shared Konstantin I. PopoviD· 1 shared Konstantin PopoviD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 26 mutual co-author links

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2 shared papersBiophysics

Brandon NovyORCID

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2 papers

Recent·Most cited

BiophysicsAnalytical ChemistryPeer-reviewedSep 12, 2025

A Hit Prioritization Strategy for Compound Library Screening Using LiP-MS and Molecular Dynamics Simulations Applied to KRas G12D Inhibitors

Foroughsadat Absar, Brandon Novy, Edith Nagy…·Christoph H. Borchers

This study combines LiP-MS and molecular dynamics simulations to prioritize KRas G12D inhibitors by analyzing cleavage site protection and binding affinity.

4 citations

proteomicsstructural biology

𝕏 PostBluesky

BiophysicsComputational and Structural Biotechnology JournalPeer-reviewedJan 1, 2025

Characterization of the KRas G12D-inhibitor interactions by HDX-MS and molecular dynamics simulations

Evgeniy V. Petrotchenko, Brandon Novy, Edith Nagy…·Christoph H. Borchers

The paper uses HDX-MS and MD simulations to analyze KRas G12D-inhibitor interactions, showing a correlation between binding affinity and structural changes.

5 citations

proteomicsexperimental assay

𝕏 PostBluesky