Konstantin Popov

This paper develops a computational pipeline to identify conserved antiviral target sites in alphaviruses using AI-driven methods, validating potential drug targets through mutagenesis.

This study combines LiP-MS and molecular dynamics simulations to prioritize KRas G12D inhibitors by analyzing cleavage site protection and binding affinity.

This paper identifies and characterizes RA-0002034, a covalent inhibitor of CHIKV nsP2 protease, showing potent inhibition and selectivity against alphaviruses.

The paper identifies potent covalent inhibitors of Chikungunya nsP2 protease and establishes structure-activity relationships to guide inhibitor design.