PhysiologybioRxivPreprint
Inhibition of p107 alleviates liver steatosis by reducing de novo fatty acid synthesis.
Juan Cuñarro, Marta Varela Miguens, Tadeu de Oliveira Diz…·Sulay A. Tovar
This study shows that inhibiting p107 reduces liver steatosis by lowering de novo fatty acid synthesis and enhancing mitochondrial function in both mouse models and human hepatocytes.