Author

Alejandro Fuentes-Iglesias

Universidade de Santiago de CompostelaORCID 0000-0002-8634-6701Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Diana GuallariD· 2 shared Miguel FidalgoiD· 2 shared Alba Cabaleiro· 1 shared Alba CoegoiD· 1 shared Alfonso MoraiD· 1 shared Ana T. MaduroiD· 1 shared Anxo VidaliD· 1 shared Carlos DiégueziD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Diana GuallarORCID

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2 papers

Recent·Most cited

The Holliday junction resolvase GEN1 preserves genome integrity and self-renewal in mouse embryonic stem cells

Lucia Ramos-Lage, Cristina Ameneiro, David Martinez-Delgado, Helena Covelo Molares, Tiago Moreira, Raquel Carreira, Diana Rubio-Contreras, Alba Coego, Vera Garcia‐Outeiral, Alejandro Fuentes-Iglesias, Evi Soutoglou, Miguel Fidalgo, Miguel G. Blanco, Diana Guallar

This study shows that GEN1 is essential for mouse embryonic stem cell self-renewal and genome stability, with a non-enzymatic role in maintaining pluripotency.

bioRxiv · Jul 23, 2026 · PreprintCell Biology

Inhibition of p107 alleviates liver steatosis by reducing de novo fatty acid synthesis.

Juan Cuñarro, Marta Varela Miguens, Tadeu de Oliveira Diz, Xabier Buqué, Lucia Oro, Cristina Riobello, Jose Iglesias-Moure, Carmen Quintela-Vilariño, Ana T. Maduro, Alba Cabaleiro, Eva Nóvoa, Alejandro Fuentes-Iglesias, Miguel Fidalgo, Diana Guallar, Anxo Vidal, , Sulay A. Tovar

This study shows that inhibiting p107 reduces liver steatosis by lowering de novo fatty acid synthesis and enhancing mitochondrial function in both mouse models and human hepatocytes.

bioRxiv · Apr 16, 2026 · PreprintPhysiology