Chananchida Sang-aram

anndataR enables interoperability between R and Python by allowing native reading and writing of H5AD files in R, with compatibility testing and conversion to R single-cell objects.

Continued allergen exposure drives lung TLO to generate ASCs that home to IL1-instructed para-bronchial cuffs.

The paper benchmarks 11 cell type deconvolution methods on spatial transcriptomics data using synthetic and real datasets, finding that some off-the-shelf methods outperform specialized ones.

Combining pseudobulk differential expression, cell-type specificity, sample prevalence and NicheNet-v2 ligand activity, MultiNicheNet ranks condition-specific ligand-receptor-target signaling in multi-sample scRNA-seq with batches or multifactor designs.