Author

Charles L. Larson

National Institute of Allergy and Infectious DiseasesORCID 0000-0002-0924-0604Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

Adam HageiD· 2 shared Byron ShueiD· 2 shared Jeffrey G. ShannoniD· 2 shared Shelly J. RobertsoniD· 2 shared Sonja M. BestiD· 2 shared Abhilash I. Chiramel· 1 shared Alison W. AshbrookiD· 1 shared Benjamin H. SchwarziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMicrobiology

Adam HageORCID

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2 papers

Recent·Most cited

MicrobiologyCommunications BiologyPeer-reviewedJul 7, 2026

Restraint of Powassan virus replication by TRIM5α facilitates viral avoidance of antiviral immunity

Rebecca M. Broeckel, Emily A. Fitzmeyer, Eva Chebishev…·Sonja M. Best

The paper investigates how TRIM5α restricts orthoflavivirus replication and identifies a mutation in POWV's NS3 gene that allows it to evade TRIM5α inhibition.

DOI 10.1038/s42003-026-10613-1

humanrat

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ImmunologyPLoS PathogensPeer-reviewedApr 21, 2025

Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine

Samantha G. Muccilli, Benjamin H. Schwarz, Byron Shue…·Sonja M. Best

This study identifies mitochondrial hyperactivity and reactive oxygen species as critical drivers of innate immunity to the YFV-17D vaccine, enhancing IFN response and vaccine effectiveness.

23 citationstop 2%

humanmetabolomics

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