Author
National Institutes of HealthORCID 0000-0003-4211-4308Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Adam Hage, Mikhaila Janes, Byron Shue…·Sonja M. Best
This study identifies NONO as a critical facilitator of antiviral innate immune response by promoting chromatin accessibility and IFN-I/ISG expression.
Rebecca M. Broeckel, Emily A. Fitzmeyer, Eva Chebishev…·Sonja M. Best
The paper investigates how TRIM5α restricts orthoflavivirus replication and identifies a mutation in POWV's NS3 gene that allows it to evade TRIM5α inhibition.
Samantha G. Muccilli, Benjamin H. Schwarz, Byron Shue…·Sonja M. Best
This study identifies mitochondrial hyperactivity and reactive oxygen species as critical drivers of innate immunity to the YFV-17D vaccine, enhancing IFN response and vaccine effectiveness.