Adam Hage

This study identifies NONO as a host factor that epigenetically regulates DPP4 expression, facilitating MERS-CoV replication by modulating histone modifications at the DPP4 locus.

This study identifies NONO as a critical facilitator of antiviral innate immune response by promoting chromatin accessibility and IFN-I/ISG expression.

The paper investigates how TRIM5α restricts orthoflavivirus replication and identifies a mutation in POWV's NS3 gene that allows it to evade TRIM5α inhibition.

This study identifies mitochondrial hyperactivity and reactive oxygen species as critical drivers of innate immunity to the YFV-17D vaccine, enhancing IFN response and vaccine effectiveness.

This study identifies TRIM7 as an E3-ubiquitin ligase that ubiquitinates SARS-CoV-2 M protein to inhibit apoptosis and viral replication.