Jamie M. Kramer

This paper shows that Bap60, a SWI/SNF complex subunit in Drosophila, is essential for long-term memory (LTM) gene transcription but not short-term memory, acting downstream of immediate early genes.

This study shows that expressing a RGNEF N-terminal fragment mitigates TDP-43 toxicity in ALS models by reducing aggregation and neurodegeneration.

This study shows that trithorax maintains long-term memory in Drosophila by preserving metabolic identity and translation capacity in mushroom body neurons.

The paper identifies six rare de novo missense variants in WDR5 associated with neurodevelopmental disorders and highlights their impact on COMPASS family protein interactions.

This study characterizes SETD1A haploinsufficiency in humans and Drosophila, identifying a novel neurodevelopmental syndrome with cognitive and developmental symptoms.

The paper analyzes the Drosophila mushroom body transcriptome at 1 hour and 24 hours post-long-term courtship memory acquisition, revealing distinct gene expression changes in the MB compared to whole head samples.

The paper identifies distinct roles for the BAP and PBAP subcomplexes of the SWI/SNF complex in memory formation and neuronal survival in Drosophila mushroom body neurons.