Author

Melissa M. Mangala

Children's Medical Research InstituteORCID 0000-0002-0924-6782Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Anai Gonzalez-CorderoiD· 2 shared Alicia A. BrunetiD· 1 shared Anna Fredericks· 1 shared Annie L. MilleriD· 1 shared David M. HuntiD· 1 shared Denise Anderson· 1 shared Di Xiao· 1 shared Emilie O Wong· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Anai Gonzalez-CorderoORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 11, 2025

Pre-clinical validation of a novel AAV-mediated gene therapy for KCNV2 retinopathy improves visual function in a mouse model and expression in patient organoids

Rabab Rashwan, Paula I. Fuller-Carter, Xin Ru Lim…·Lívia S. Carvalho

This paper demonstrates that AAV-mediated gene therapy restores retinal function and KCNV2 expression in a mouse model of KCNV2 retinopathy and human retinal organoids.

DOI 10.64898/2025.12.09.692426

mousehuman

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Developmental BiologybioRxivPreprintJul 9, 2025

Refate identifies chemical compounds to target trans-regulatory networks for cellular conversion

Di Xiao, Sonu Sahadevan, Melissa M. Mangala…·Pengyi Yang

Refate identifies chemical compounds targeting trans-regulatory networks to enable cellular conversion by integrating single-cell data and drug databases.

DOI 10.1101/2025.07.09.664003

humanscRNA-seq

𝕏 PostBluesky