Rob Barringer

This paper designs de novo flavoproteins with controlled excited state dynamics using computational methods and experimental validation.

This study identifies AnkA as a bacterial effector that directly targets the WAVE Regulatory Complex and actin cytoskeleton, using molecular mimicry to subvert host cell functions during infection.

This paper designs redox proteins with tunable electron transfer properties by replacing heme B with non-natural metalloporphyrins, achieving redox potential modulation of over 400 mV.

The paper identifies and characterizes intramolecular isopeptide bonds in protein domains across organisms, revealing their structural and functional significance.

Isopeptor detects intramolecular isopeptide bonds in protein structures using structure-guided template matching and logistic regression, achieving high recall and precision on a curated PDB subset.