Author

Roland Roelz

University of FreiburgORCID 0000-0002-0985-7583Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2

Frequent Co-Authors

Kevin JosephiD· 3 shared Vidhya Madapusi RaviiD· 3 shared Ioannis VasilikosiD· 2 shared Juergen GrauvogeliD· 2 shared Marco PrinziD· 2 shared Mohammad Al Shhab· 2 shared Nishitha S Ghariwala· 2 shared Vatsal D. JariwalaiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

Kevin JosephORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 3, 2026

Spatially confined niches support hypoxia-associated transcriptional plasticity contributing to malignant progression in IDH-mutant gliomas

Depro Das, Alina Pandele, Vatsal D. Jariwala…·Sajib Chakraborty

This study identifies hypoxia-associated transcriptional plasticity in IDH-mutant gliomas, showing microglia-driven quiescent-to-activated transitions that drive malignant progression.

DOI 10.64898/2026.05.31.729105

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 28, 2026

Hypoxia and Associated Acidosis Generate Cell-Type Specific Myeloid Responses in Glioblastoma

Aliisa M. Tiihonen, Iida Salonen, Iina Koivisto…·Kirsi J. Rautajoki

The paper investigates how hypoxia and acidosis influence myeloid cell responses in glioblastoma, revealing distinct metabolic adaptations in macrophages versus microglia.

1 citation

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 24, 2025

Iron-Associated Mesenchymal Plasticity and Tumor Invasion in Glioblastoma

Christophe Petry, Ambra-Stella Boecke, Aso Omer Mohammed…·Vidhya Madapusi Ravi

This study identifies an iron-associated mesenchymal subpopulation in GBM that drives invasion and is linked to poor patient survival.

DOI 10.64898/2025.12.22.695920

humanscRNA-seq

𝕏 PostBluesky