Author

Gabriela Hoffman

ATDBio (United Kingdom)ORCID 0000-0002-0986-4310Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adam P. CribbsiD· 2 shared Danson Shek Chun LoiiD· 2 shared Jianfeng SuniD· 2 shared Jonathan Robson· 2 shared Martin PhilpottiD· 2 shared Neelam Mehta· 2 shared Udo C. T. OppermanniD· 2 shared Vicki Gamble· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersMolecular Biology

Adam P. CribbsORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 8, 2024

Anchor-Enhanced Bead Design for Reduced Oligonucleotide Synthesis Errors in Single-cell sequencing

Jianfeng Sun, Martin Philpott, Danson Shek Chun Loi…·Adam P. Cribbs

The paper introduces an anchor-enhanced bead design to reduce oligonucleotide synthesis errors in single-cell sequencing, improving UMI recovery and feature detection.

2 citations

scRNA-seqexperimental assay

𝕏 PostBluesky

GenomicsbioRxivPreprintApr 6, 2023

Correcting PCR amplification errors in unique molecular identifiers to generate absolute numbers of sequencing molecules.

Jianfeng Sun, Martin Philpott, Danson Shek Chun Loi…·Adam P. Cribbs

The paper demonstrates that PCR errors significantly affect UMI-based absolute counting in sequencing data and proposes a solution using homotrimeric nucleotide blocks to correct these errors.

2 citations

bulk RNA-seqscRNA-seq

𝕏 PostBluesky