Author

Jonathan Robson

ATDBio (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adam P. CribbsiD· 2 shared Danson Shek Chun LoiiD· 2 shared Gabriela HoffmaniD· 2 shared Jianfeng SuniD· 2 shared Martin PhilpottiD· 2 shared Neelam Mehta· 2 shared Udo C. T. OppermanniD· 2 shared Vicki Gamble· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersMolecular Biology

Adam P. CribbsORCID

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2 papers

Recent·Most cited

Anchor-Enhanced Bead Design for Reduced Oligonucleotide Synthesis Errors in Single-cell sequencing

Jianfeng Sun, Martin Philpott, Danson Shek Chun Loi, Gabriela Hoffman, Jonathan Robson, Neelam Mehta, Eleanor Calcutt, Vicki Gamble, Tom P Brown, Udo C. T. Oppermann, Adam P. Cribbs

The paper introduces an anchor-enhanced bead design to reduce oligonucleotide synthesis errors in single-cell sequencing, improving UMI recovery and feature detection.

bioRxiv · Apr 8, 2024 · PreprintMolecular Biology

Correcting PCR amplification errors in unique molecular identifiers to generate absolute numbers of sequencing molecules.

Jianfeng Sun, Martin Philpott, Danson Shek Chun Loi, Shuang Li, Pablo Monteagudo-Mesas, Gabriela Hoffman, Jonathan Robson, Neelam Mehta, Vicki Gamble, Tom Brown, Stefan Canzar, Udo C. T. Oppermann, Adam P. Cribbs

The paper demonstrates that PCR errors significantly affect UMI-based absolute counting in sequencing data and proposes a solution using homotrimeric nucleotide blocks to correct these errors.

bioRxiv · Apr 6, 2023 · PreprintGenomics