Janina P. Lewis

This study shows Hcp enables Porphyromonas gingivalis survival in nitrate-reducing biofilms by mediating nitrosative stress resistance, revealing RNS as a key ecological factor shaping oral microbiome interactions.

This study determines the structure of HcpR from Porphyromonas gingivalis and identifies key residues involved in heme binding and activation.

This paper identifies PG0785 as a TonB protein in Porphyromonas gingivalis and shows it is not involved in nutrient acquisition but in protease maturation and cell surface remodeling.

This study shows that inhibiting SUMOylation with TAK-981 stabilizes cBAF complexes and disrupts the SS18::SSX-driven transcriptome in synovial sarcoma, leading to tumor inhibition.