Author

Alexandros C. Dimopoulos

Harokopio University of AthensORCID 0000-0002-4602-2040Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Afroditi SotiriouiD· 1 shared Agoritsa Kalampaliki· 1 shared Ana BanitoiD· 1 shared Anastasia KritharaiD· 1 shared Anastasios NentidisiD· 1 shared Andrew Stewart PoklepoviciD· 1 shared Angeliki M. Stamatouli· 1 shared Anthony C. FaberiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

Afroditi SotiriouORCID

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3 papers

Recent·Most cited

Mapping the AI Life Sciences Landscape in Greece: A National Survey and Bibliometric Comparison with Global Trends

Eleni S. Adamidi, Serafeim Chatzopoulos, Alexandros C. Dimopoulos, Anastasia Krithara, Anastasios Nentidis, Nikolaos Pechlivanis, Fotis E Psomopoulos, Thanasis Vergoulis, Kleanthis Vichos

This study maps AI use in Greek Life Sciences through bibliometric analysis and a national survey, revealing strengths in methodology and barriers in data and resources.

bioRxiv · Nov 19, 2025 · PreprintBioinformatics

Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma

Konstantinos V. Floros, Carter K. Fairchild, Jinxiu Li, Kun Zhang, Jane L. Roberts, Richard Kurupi, Durga Paudel, Yanli Xing, Bin Hu, Vita Kraskauskiene, Nayyerehalsadat Hosseini, Shanwei Shen, Melissa M. Inge, Kyllie Smith-Fry, Li Li, , Anthony C. Faber

This study shows that inhibiting SUMOylation with TAK-981 stabilizes cBAF complexes and disrupts the SS18::SSX-driven transcriptome in synovial sarcoma, leading to tumor inhibition.

Nature Communications · Nov 5, 2025Peer-reviewedCancer Biology

A Root Mean Square Deviation Estimation Algorithm (REA) and its use for improved RNA Structure Prediction

Agoritsa Kalampaliki, Alexandros C. Dimopoulos, Martin Reczko

The paper introduces REA, a neural network to predict RNA structure RMSD, outperforming existing methods and improving prediction accuracy when combined with SVR.

bioRxiv · Feb 28, 2024 · PreprintBioinformatics