Cancer BiologyScience AdvancesPeer-reviewed
Nectin-4 PET For Optimizing Enfortumab Vedotin Dose-Response In Urothelial Carcinoma
Akhilesh Mishra, Ajay Sharma, Kuldeep Gupta…·Sridhar Nimmagadda
This paper uses Nectin-4 PET imaging to assess target engagement and optimize dosing of enfortumab vedotin in urothelial carcinoma, finding that PET metrics better predict therapeutic response than dose or baseline expression.