Burles Avner Johnson

The paper develops a murine model of sarcomatoid urothelial carcinoma (SUC) and finds it shares molecular and immunological features with human SUC, suggesting its use for therapeutic research.

This study compares the biology and genetic drivers of human and canine invasive urothelial carcinoma, finding shared cellular organization but distinct mutations and platform effects in organoids.

This paper uses Nectin-4 PET imaging to assess target engagement and optimize dosing of enfortumab vedotin in urothelial carcinoma, finding that PET metrics better predict therapeutic response than dose or baseline expression.