Trishla Sinha

Comprehensive profiling of infant gut virome assembly reveals associations with eczema and wheeze

This study profiles the infant gut virome using dual methods and finds associations with eczema and wheeze.

Pregnancy and Early-Life Gut Virome in the Lifelines NEXT cohort:Origin, Persistence, Influencing Factors and Health Implications

The paper analyzes the gut virome in mother-infant pairs to identify factors influencing its development and persistence, finding that delivery mode and breastmilk shape the infant virome and that viral diversity is linked to food allergies.

Prophages of infant-derived Bifidobacterium longum subspecies employ antagonistic and synergistic strategies to persist in their host

The paper identifies and analyzes prophages in infant-derived Bifidobacterium longum subspecies, revealing their antagonistic and synergistic strategies for persistence in the gut.

Discovery, functionality and global dynamics of Bifidobacterium longum subsp. nexti : a novel starch-degrading subspecies in the infant gut

The paper identifies a novel subspecies of Bifidobacterium longum, BL. nexti, in infant gut microbiomes, showing its association with formula feeding and vertical transmission.

Dynamics and determinants of the gut mobilome in early life

The paper analyzes the gut mobilome in mother-infant dyads, finding increased infant mobilome richness over time, formula feeding effects, and antibiotic resistance gene presence in plasmids.

Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project

The paper identifies host genetic loci associated with gut microbiome composition and function in a large cohort, finding significant associations near LCT and ABO genes.