Author

Martin Oti

Boehringer Ingelheim (Germany)ORCID 0000-0002-1005-5801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Benjamin StrobeliD· 1 shared Christian Schön· 1 shared Colin LogieiD· 1 shared Ellen H. J. van den BogaardiD· 1 shared Evelyn N. Kouwenhoven· 1 shared Hans van BokhoveniD· 1 shared Hendrik G. StunnenbergiD· 1 shared Huiqing ZhouiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Benjamin StrobelORCID

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2 papers

Recent·Most cited

STARR-CRAAVT: A platform to design cell type-specific regulatory elements for next-generation gene therapy

Robert Becker, Priyanka Choudhury, Martin Oti, Youssef Fouani, Benjamin Strobel, Stephanie Ketterer, Simon Rumpel, John Park, Sebastian Kreuz, Udo Maier, Stefan Michelfelder, Christian Schön

This study introduces STARR-CRAAVT, a platform to identify cell type-specific enhancers for gene therapy, showing promoter preference and enhancer positioning significantly affect activity.

bioRxiv · Jun 4, 2025 · PreprintGenomics

Mutant p63 affects epidermal cell identity through rewiring the enhancer landscape

Jieqiong Qu, Sabine E.J. Tanis, Jos P.H. Smits, Evelyn N. Kouwenhoven, Martin Oti, Ellen H. J. van den Bogaard, Colin Logie, Hendrik G. Stunnenberg, Hans van Bokhoven, Klaas W. Mulder, Huiqing Zhou

This study investigates how p63 mutations alter the enhancer landscape in epidermal keratinocytes, affecting cell identity through changes in gene regulation.

Cell Reports · Dec 1, 2018Peer-reviewedMolecular Biology