Author
Radboud University Nijmegen
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Niels Krämer, Roderick A. P. M. van Eijl, Tim Stohn…·Klaas W. Mulder
The paper investigates how cell-state differences affect drug responses and signaling network interactions in human epidermal stem cells.
Jan P. Gerlach, Jessie A.G.L. van Buggenum, Sabine E.J. Tanis…·Klaas W. Mulder
The paper introduces RAID, a method to analyze both transcriptomes and intracellular phosphoproteins from fixed single cells, showing its ability to detect heterogeneity in cellular responses.
Jieqiong Qu, Sabine E.J. Tanis, Jos P.H. Smits…·Huiqing Zhou
This study investigates how p63 mutations alter the enhancer landscape in epidermal keratinocytes, affecting cell identity through changes in gene regulation.
Sabine E.J. Tanis, Pascal W.T.C. Jansen, Huiqing Zhou…·Klaas W. Mulder
The paper identifies ZMAT2 as a regulator of human epidermal differentiation through interactions with epigenetic modifiers and the pre-spliceosome, highlighting joint control of cell adhesion genes.
Roderick A. P. M. van Eijl, Jessie A.G.L. van Buggenum, Sabine E.J. Tanis…·Klaas W. Mulder
The paper uses single-cell ID-seq to identify BMP signaling as a driver of late-stage epidermal differentiation by analyzing phospho-specific epitopes and transcription factors.
Jessie A.G.L. van Buggenum, Jan P. Gerlach, Sabine E.J. Tanis…·Klaas W. Mulder
The paper introduces ID-seq, a technology that measures multiple molecular and cellular phenotypes in parallel, and uses it to study kinase inhibitor effects on human epidermal stem cells.