DAF-16/Foxo suppresses the transgenerational sterility of prg-1 piRNA mutants via a systemic small RNA pathway
Matt Simon, Maya Spichal, Bree Heestand…·Shawn Cameron Ahmed
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University of North Carolina at Chapel HillORCID 0000-0002-1043-1715Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Matt Simon, Maya Spichal, Bree Heestand…·Shawn Cameron Ahmed
Maya Spichal, Bree Heestand, Katherine Kretovich Billmyre…·Shawn Cameron Ahmed
The paper shows that defects in Piwi and germ granules in C. elegans lead to reproductive arrest through altered germ granules, not transposon activation, causing sterility.
Katherine Kretovich Billmyre, Anna-Lisa Doebley, Maya Spichal…·Shawn Cameron Ahmed
This paper identifies a meiosis-specific function of the phosphatase GSP-2 in promoting germ cell immortality through small RNA-mediated genome silencing in C. elegans.