Shawn Cameron Ahmed

The paper shows that small RNA-mediated genomic silencing maintains telomere stability in C. elegans without telomerase by promoting heterochromatin formation and subtelomeric small RNA biogenesis.

The paper shows that prg-1 mutant C. elegans germ cells transmit heritable stress that promotes longevity but reduces fertility, with effects observed in F1 progeny.

The paper investigates the roles of RTEL-1 and DNA polymerase theta in subtelomeric DNA synthesis and telomere fusion in C. elegans, finding they promote these processes through distinct mechanisms.

The paper shows that defects in Piwi and germ granules in C. elegans lead to reproductive arrest through altered germ granules, not transposon activation, causing sterility.

The paper engineers threshold-based selection systems in C. elegans to identify novel downstream effectors by disrupting embryonic morphogenesis with conditional CED-10/Rac activation.

This study shows that C. elegans POT-1 proteins regulate telomeric foci in gametes across generations without affecting telomere length.

The paper identifies telomeric small RNAs in Caenorhabditis species, showing that mismatched variants mostly originate from ITSs while perfect repeats are rare in C. elegans but abundant in C. briggsae and C. remanei.

This paper identifies a meiosis-specific function of the phosphatase GSP-2 in promoting germ cell immortality through small RNA-mediated genome silencing in C. elegans.