Author

Leonard O. Marque

Johns Hopkins UniversityORCID 0000-0002-1045-2321Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Christopher A. RossiD· 1 shared Dobrila D. Rudnicki· 1 shared Erin Hedglen· 1 shared Ho Yin Edwin ChaniD· 1 shared Hongxuan Feng· 1 shared Jing JiniD· 1 shared Nicolas ArbeziD· 1 shared Pan P. LiiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Christopher A. RossORCID

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1 paper

Recent·Most cited

NeuroscienceMovement DisordersPeer-reviewedAug 14, 2021

RNA toxicity and perturbation of rRNA processing in spinocerebellar ataxia type 2

Pan P. Li, Roumita Moulick, Hongxuan Feng…·Dobrila D. Rudnicki

This study shows that expanded ATXN2 transcripts are toxic and disrupt rRNA processing in SCA2, similar to expanded HTT transcripts in HD, suggesting a shared mechanism in repeat expansion diseases.

18 citations

humanbulk RNA-seq

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