Author

Dobrila D. Rudnicki

Johns Hopkins University

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Christopher A. RossiD· 1 shared Erin Hedglen· 1 shared Ho Yin Edwin ChaniD· 1 shared Hongxuan Feng· 1 shared Jing JiniD· 1 shared Leonard O. MarqueiD· 1 shared Nicolas ArbeziD· 1 shared Pan P. LiiD· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperNeuroscience

Christopher A. RossORCID

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1 paper

Recent·Most cited

NeuroscienceMovement DisordersPeer-reviewedAug 14, 2021

RNA toxicity and perturbation of rRNA processing in spinocerebellar ataxia type 2

Pan P. Li, Roumita Moulick, Hongxuan Feng…·Dobrila D. Rudnicki

This study shows that expanded ATXN2 transcripts are toxic and disrupt rRNA processing in SCA2, similar to expanded HTT transcripts in HD, suggesting a shared mechanism in repeat expansion diseases.

18 citations

humanbulk RNA-seq

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