Sönke Cordeiro

The paper identifies Mangostin as a BK channel activator that induces vasorelaxation by modulating key S6 domain residues.

This study identifies the C-terminal domain as the temperature sensor in TREK channels and shows that microtubule interaction and PKA phosphorylation regulate their thermosensitivity.

The paper presents a cryoEM structure of the human THIK-1 K2P K+ channel, revealing structural features and regulatory mechanisms involving lipids and anaesthetics.