Marianne A. Musinszki

Down- to up-state transition is the default pathway in TREK K2P channel activation and does not involve a lipid occluded pore

The paper identifies the down-to-up state transition as the primary activation pathway for TREK K2P channels, showing it does not involve lipid occlusion of the pore.

Natural xanthones as α-Mangostin induce vasorelaxation involving key gating residues in the S6 domain of BK channels

The paper identifies Mangostin as a BK channel activator that induces vasorelaxation by modulating key S6 domain residues.

Thermosensitivity of TREK K2P channels is controlled by a PKA switch and depends on the microtubular network

This study identifies the C-terminal domain as the temperature sensor in TREK channels and shows that microtubule interaction and PKA phosphorylation regulate their thermosensitivity.